目的 探析在血液净化护理中心理护理的应用效果及对患者负面情绪的影响.方法 研究样本限定为本院2019年1月～2020年12月收治的开展血液透析治疗的56例患者,根据护理形式的不同分为两组,即对照组与观察组,每组的样本容量均为28例.对照组采取常规护理,观察组基于此增加心理护理,就两组的焦虑与抑郁评分、睡眠质量、护理依从性、护理满意度、生活质量进行对比分析.结果 护理前两组的焦虑与抑郁评分、睡眠质量、护理依从性、护理满意度、生活质量等指标比较差异不明显,P＞0.05.护理后,两组焦虑与抑郁评分均低于护理前,且观察组焦虑评分23.15±2.25分、抑郁评分24.25±2.51分低于对照组,P＜0.05.护理后,两组睡眠质量评分低于护理前,且观察组睡眠质量评分5.41±1.20分低于对照组的7.35±1.60分,P＜0.05.观察组血糖监测、合理饮食、运动训练、按时用药等护理依从性评分分别为93.45±2.15分、94.24±2.28分、95.15±1.27分、94.24±2.88分,均高于对照组,P＜0.05.观察组护理总满意度96.43％高于对照组的71.43％,P＜0.05.护理后,两组生活质量评分高于护理前,且观察组社会能力94.24±4.51分、心理情绪94.64±5.24分、身体疼痛90.45±2.45分、活动能力91.54±2.15分,均高于对照组,P＜0.05.结论 针对血液净化患者采用心理护理可取得显著的护理效果,可以减轻患者负面情绪,改善睡眠质量,又能提高患者的护理依从性与护理满意度,在提升生活质量中具有积极作用,值得临床推广.“,”Objective To analyze the application effect of psychological nursing in blood purification nursing and its influence on patients\'\' negative emotions. Methods The study sample was limited to 56 patients who were admitted to our hospital for hemodialysis treatment from January 2019 to December 2020. They were divided into two groups according to the different forms of care, namely the control group and the observation group, the sample size of each group all were 28 cases. The control group took routine care, and the observation group added psychological care based on this. The two groups\'\' anxiety and depression scores, sleep quality, nursing compliance, nursing satisfaction, and quality of life were compared and analyzed. Results There was no significant difference in the scores of anxiety and depression, sleep quality, nursing compliance, nursing satisfaction, quality of life and other indicators between the two groups before nursing, P＞0.05. After nursing, the anxiety and depression scores of the two groups were lower than those before nursing, and the anxiety score 23.15±2.25 and depression score 24.25±2.51 of the observation group were lower than those of the control group, P＜0.05. After nursing, the sleep quality scores of the two groups were lower than those before nursing, and the sleep quality scores of the observation group 5.41±1.20 were lower than those of the control group 7.35±1.60, P＜0.05. The observation group\'\'s nursing compliance scores such as blood glucose monitoring, reasonable diet, exercise training, and regular medication were 93.45±2.15 points, 94.24±2.28 points, 95.15±1.27 points, 94.24±2.88 points, respectively, all high In the control group, P＜0.05. The total nursing satisfaction of the observation group was 96.43％ higher than that of the control group 71.43％, P＜0.05. After nursing, the quality of life scores of the two groups were higher than those before nursing, and the observation group had scores of social ability 94.24±4.51, psychological and emotional 94.64±5.24, physical pain 90.45±2.45, and activity ability 91.54±2.15, the scores were higher than those of the control group, P＜0.05. Conclusion The use of psychological care for blood purification patients can achieve significant nursing effects, reduce patients\'\' negative emotions, improve sleep quality, and improve nursing compliance and nursing satisfaction. It plays a positive role in improving the quality of life and is worthy of clinical promotion.