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目的 了解孕妇麻疹免疫状况和婴儿麻疹疫苗免疫效果。方法 对 1 1 2名孕妇产前和5 0名 6月龄婴儿及 72名 8月龄婴儿免前免后采用酶联免疫吸附试验 (ELISA)检测麻疹抗体IgG。结果 1 1 2名孕妇麻疹抗体阳性 1 0 7例 ,阳性率 95 5 % ,抗体滴度 (GMRT)为 84 9 9;未达到保护水平有 30例 ,占 2 6 8% ;6月龄和 8月龄婴儿免疫成功率分别为 88 0 %、97 2 % ,免前麻疹抗体GMRT分别为4 1、1 1 ,差异均有显著性 (均P <0 0 5 ) ,而免后麻疹抗体GMRT分别为 782 0、976 5 ,差异无显著性(P >0 0 5 )。结论 8月龄婴儿免疫效果稍好于 6月龄婴儿 ,主要表现在免疫成功率方面 ,而免后抗体水平差异无显著性。
Objective To understand the immune status of measles in pregnant women and the immunization effect of infant measles vaccine. Methods 112 cases of pregnant women prenatal and 50 0 6 month old infants and 72 8 month old infants were immunized with enzyme immunoassay (ELISA) to detect measles antibody IgG. RESULTS: The positive rate of measles antibody in pregnant women was 107 (95.5%), the antibody titer (GMRT) was 84 9 9, 30 cases did not reach the level of protection (26.8%), 6 months old and 8 The infant immunization success rates at month-old were 88.0% and 97.2%, respectively. The GMRT of pre-immune measles antibody was 41.1% (all P <0.05), while the post-immunization measles antibody GMRT was 782 0,976 5, the difference was not significant (P> 0.05). Conclusion The immunization efficacy of 8-month-old infants is slightly better than that of 6-month-old infants, which is mainly reflected in the success rate of immunization, but no significant difference in antibody levels after immunization.