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目的:探讨糖皮质激素在急性呼吸窘迫综合症(ARDS)治疗中的意义及进展。方法:回顾性分析我科采用大剂量甲泼尼龙救治的1例结缔组织病合并ARDS高龄患者诊治过程,并结合文献进行复习。结果:患者采用大剂量甲泼尼龙治疗后,有效改善肺部功能,减轻肺纤维化。随访至今病情稳定。结论:在ARDS治疗过程中,激素发挥重要作用,激素剂量及疗程的应用需因病而异。
Objective: To investigate the significance and progress of glucocorticoids in the treatment of acute respiratory distress syndrome (ARDS). Methods: One case of connective tissue disease complicated with ARDS in elderly patients treated with high-dose methylprednisolone was retrospectively analyzed and reviewed in combination with the literature. Results: The patients treated with high-dose methylprednisolone effectively improved lung function and alleviated pulmonary fibrosis. Follow-up is stable. Conclusions: Hormones play an important role in the treatment of ARDS. The dosage of hormones and the course of treatment need to be different depending on the disease.