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糖尿病的药物治疗,除了前期我们介绍的胰岛素,就是品类繁多的口服降糖药物了。在所有的口服降糖药物中,二甲双胍是最具有历史感的药物。自1957年上市以来,二甲双胍已经风风雨雨走过了近六十年,成为糖尿病治疗里程中一个不老的神话。今天,我就将带领读者朋友们一起探寻二甲双胍的故事。一、二甲双胍的发现及历史神话故事,总有充满奇幻色彩的故事源头,二甲双胍当然也不例外。双胍的发现有点类似于2015年我国首个诺贝尔医学奖的获得者屠呦呦的青蒿素,充满着传奇的色彩。在中世纪的时候,人们发现当
Drug treatment of diabetes, in addition to the insulin we introduced earlier, is a wide range of oral hypoglycemic drugs. Among all oral hypoglycemic agents, metformin is the most historic drug. Since its listing in 1957, metformin has been a thunderstorm for almost 60 years and has become an old myth in the treatment of diabetes mellitus. Today, I will lead readers and friends to explore the story of metformin. First, the discovery of metformin and historical myths, there are always full of fantastic sources of the story, of course metformin is no exception. The discovery of biguanide is somewhat similar to that of Artemisinin Tu Yo-Yo, winner of the first Nobel Prize in Medicine in China in 2015, full of legendary colors. In the Middle Ages, people discovered when