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目的:研究慢性阻塞性肺气肿患者加重期治疗过程中选择的抗菌药物,本文主要是比较头孢呋辛和左氧氟沙星的临床治疗效果,以其为临床提供更好的治疗方案。方法:我院选择2012年9月-2013年9月间诊治的80例慢性阻塞性肺疾病急性加重期患者,将其分为两组,组1的40例患者运用头孢呋辛进行治疗,组2的40例患者运用左氧氟沙星进行治疗,每治疗2周比较1次,观察两组患者的临床治疗效果。结果:通过对两组患者进行比较,组1的40例患者中,20例显效,12例有效,8例无效,有效率为80.00%;组2的40例患者中,26例显效,10例有效,4例无效,有效率为90.00%;两组患者治疗有效率差异显著,有统计学意义(P<0.05)。组1患者中有6例在服药后出现胃肠道反应,组2患者中有4例出现头痛症状,两组患者差异显著,有统计学意义(P<0.05)。结论:慢性阻塞性肺疾病患者处于急性加重期时运用左氧氟沙星治疗的临床效果更加明显,而且患者出现的不良反应较少,值得在临床上推广使用。
OBJECTIVE: To study the antimicrobial agents selected during the treatment of patients with chronic obstructive pulmonary emphysema. In this paper, the clinical efficacy of cefuroxime and levofloxacin is compared with that of cefuroxime to provide a better clinical treatment. Methods: Eighty patients with acute exacerbation of chronic obstructive pulmonary disease who were diagnosed and treated in our hospital from September 2012 to September 2013 were divided into two groups: 40 patients in group 1 were treated with cefuroxime, 2 of 40 patients with levofloxacin treatment, compared to two weeks each treatment 1 times, the clinical efficacy of two groups were observed. Results: Of the 40 patients in group 1, 20 were effective, 12 were effective, 8 were ineffective, and the effective rate was 80.00%. Among the 40 patients in group 2, 26 were markedly effective and 10 4 cases were ineffective and the effective rate was 90.00%. There was significant difference between the two groups in the treatment efficiency (P <0.05). Six of the patients in group 1 developed gastrointestinal reactions after taking the medication. Four patients in group two had headache symptoms. There was significant difference between the two groups (P <0.05). Conclusion: The clinical effect of levofloxacin treatment in patients with chronic obstructive pulmonary disease in acute exacerbation period is more obvious, and patients have fewer adverse reactions, which is worth to be popularized in clinic.