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目的观察琥珀酸亚铁治疗缺铁性贫血的临床效果。方法选取医院门诊及住院治疗的缺铁性贫血患者94例,随机分为观察组和对照组,每组47例。观察组采用琥珀酸亚铁进行治疗,对照组采用硫酸亚铁进行治疗。观察2组患者临床疗效及药物不良反应发生情况。结果观察组显效率和总有效率分别为74.47%和100%,高于对照组的34.04%和89.36%(P均<0.05);观察组不良反应发生率为4.26%,低于对照组的29.79%(P<0.05)。2组均未出现急性中毒、休克等严重不良反应情况。结论琥珀酸亚铁对于缺铁性疾病的治疗效果显著优于硫酸亚铁,且显效率较高、不良反应相对较少、安全性更高、实用性高,值得临床推广应用。
Objective To observe the clinical efficacy of ferrous succinate in the treatment of iron deficiency anemia. Methods A total of 94 iron deficiency anemia patients were selected from outpatient department and inpatient hospital, and randomly divided into observation group and control group, with 47 cases in each group. The observation group was treated with ferrous succinate, while the control group was treated with ferrous sulfate. The clinical efficacy and adverse drug reactions in two groups were observed. Results The effective rate and total effective rate of the observation group were 74.47% and 100% respectively, which were higher than 34.04% and 89.36% of the control group (all P <0.05). The incidence of adverse reactions in the observation group was 4.26%, which was lower than that of the control group % (P <0.05). There was no serious adverse reactions such as acute poisoning and shock in the two groups. Conclusions Ferrous succinate is superior to ferrous sulphate in the treatment of iron deficiency diseases. It has higher effective rate, less adverse reactions, higher safety and higher practicability. It is worthy of clinical application.