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硬皮病是一种以局限性或弥漫性皮肤及内脏器官结缔组织的纤维化或硬化,最后发生萎缩为特点的疾病。近年来,发现硬皮病每种自身抗体的出现均代表了一种临床亚类。其临床表现不同,其中累及肾脏的,近年来国内外有报道,但主要集中在对血清自身抗体的研究,而对肾脏结构的变化观察甚少。我们对31例临床确诊为硬皮病病人肾结构进行超声检测,借以探测硬皮病病人肾结构的变化与肾功能相关性。
Scleroderma is a disease characterized by fibrosis or cirrhosis of the connective tissue of a localized or diffuse cutaneous and visceral organ, and finally atrophy. In recent years, the discovery of each autoantibody in scleroderma represents a clinical subclass. The clinical manifestations of different, including kidney involvement, in recent years at home and abroad have been reported, but mainly concentrated on the study of serum autoantibodies, and little change in the structure of the kidneys observed. We examined 31 patients with clinically diagnosed as sclerodermic renal structure of patients with ultrasound detection, in order to detect changes in renal structural scleroderma patients and renal function.