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目的:探讨引起药物性肝病的药物因素及预防对策。方法:对我院2006年1月～2009年10月75例药物性肝病患者的临床资料进行分析。结果:引起75例药物性肝病的药物依次为中药、抗结核药、解热镇痛药、抗精神病药、抗微生物药、降糖药、激素类药物、免疫抑制剂、心血管药物、抗代谢药。结论:临床医师和药师应合理用药,预防药物性肝病的发生。
Objective: To explore the drug-induced liver disease caused by drugs and preventive measures. Methods: The clinical data of 75 patients with drug-induced liver disease in our hospital from January 2006 to October 2009 were analyzed. Results: The drugs causing 75 cases of drug-induced liver disease were Chinese medicine, anti-TB drugs, antipyretic and analgesic drugs, antipsychotics, antimicrobials, hypoglycemic agents, hormone drugs, immunosuppressants, cardiovascular drugs, antimetabolites medicine. Conclusion: Clinicians and pharmacists should be rational use of drugs to prevent the occurrence of drug-induced liver disease.