随着经济增长,环境的污染、不健康的生活方式等使脑血管病的发病率日益增高,其中缺血性占大多数。研究人员依据需要制造出不同的脑缺血动物模型,并不断地进行改良。笔者为了方便研究者制造更好的动物模型以应用在不同领域,将近十年来的各种改良方法进行比较,就现在最为实行的大脑中动脉闭塞(Middle cerebral artery occlusion,MCAO)模型制造方法的优劣综述和探讨。 With the economic growth, environmental pollution, unhealthy lifestyles so that the incidence of cerebrovascular disease is increasing, of which the majority of ischemic. Researchers based on the need to create different animal models of cerebral ischemia, and continue to be improved. In order to make it easier for researchers to make better animal models to apply in different fields and to compare various improved methods in recent ten years, the author put forward that the most effective method for manufacturing middle cerebral artery occlusion (MCAO) Bad summary and discussion.