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[目的]探讨杭州市萧山区20～60岁常住妇女人乳头瘤病毒(HPV)的感染现状、型别及相关影响因素。[方法]采用多阶段分层随机抽样方法,在浙江省杭州市萧山区26个镇中抽取9个镇的27个样本行政村20～60岁常住妇女4446人进行问卷调查、妇科检查及宫颈HPV检测。[结果]HPV感染率为10.39%(462/4446),其中HR-HPV感染率为9.69%(431/4446)。HPV感染居前5位的分别是HPV52、16、58、33和18,感染率分别为2.50%、2.14%、1.80%、0.94%和0.88%。影响HPV感染的相关因素分析显示年龄、怀孕次数、人工流产次数、近3年每月性生活次数、文化程度与HPV感染无显著性相关(P>0.05);随着宫颈糜烂面积的增大,HPV感染率有逐渐上升趋势,但差异无统计学意义(P>0.05)。[结论]杭州市萧山区20～60岁常住妇女的HPV感染率为10.39%,其中HR-HPV感染率为9.69%,感染率居前5位的分别是HPV52、16、58、33和18。
[Objective] To investigate the status, types and related factors of human papillomavirus (HPV) infection among 20 ~ 60-year-old women in Xiaoshan District of Hangzhou City. [Methods] The multistage stratified random sampling method was used to survey 2946 women aged 20 ~ 60 in 27 towns in 26 towns of Xiaoshan District of Hangzhou City, Zhejiang Province for questionnaire survey, gynecological examination and cervical HPV Detection. [Results] The infection rate of HPV was 10.39% (462/4446), and the HR-HPV infection rate was 9.69% (431/4446). The top five HPV infections were HPV52, HPV16, HPV8, HPV3 and HPV8, the infection rates were 2.50%, 2.14%, 1.80%, 0.94% and 0.88% respectively. Analysis of relevant factors affecting HPV infection showed that age, number of pregnancies, number of induced abortions, number of monthly sexual lives in the past three years and education level were not significantly correlated with HPV infection (P> 0.05). With the increase of cervical erosion area, HPV infection rate has gradually increased, but the difference was not statistically significant (P> 0.05). [Conclusion] The HPV infection rate of the women aged 20 ~ 60 in Xiaoshan District of Hangzhou City was 10.39%. The infection rate of HR-HPV was 9.69%. The top five infection rates were HPV52, HPV16, HPV8, HPV3.3 and HPV18.