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西地那非是一环磷酸鸟苷依赖的 5型磷酸二酯酶的选择性抑制剂 ,用于治疗男性性功能障碍 ,其商品名为伟哥 ( Viagra)。本文综述了西地那非的药理作用及作用机制、药代动力学、临床应用和不良反应
Sildenafil is a cyclic guanosine-dependent selective inhibitor of phosphodiesterase type 5 for the treatment of male sexual dysfunction under the trade name Viagra. This review summarizes the pharmacological effects and mechanisms of sildenafil, pharmacokinetics, clinical application and adverse reactions