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目的 探讨胸腺瘤合并重症肌无力 (MG)手术治疗方法及预后。方法 对 6 3例胸腺瘤合并MG患者的手术治疗进行回顾性分析。结果 手术完全切除 5 2例 (82 5 % ) ,无手术死亡。术后 5年、10年生存率分别为 6 9 4%、5 1 6 % ,非浸润性胸腺瘤组分别为 79 4%、5 8 3 % ,浸润性组分别为 46 7%、2 8 6 % ,Ⅰ和Ⅱ期分别为 76 9%、5 7 8% ,Ⅲ和Ⅳ期分别为 40 0 %、2 0 0 %。结论 胸腺瘤合并MG的预后与Masaoka临床分期、组织学分型及手术切除的彻底性等明显相关 ,围手术期的处理和Osserman分型也影响手术的疗效及预后
Objective To investigate the surgical treatment and prognosis of thymoma combined with myasthenia gravis (MG). Methods A retrospective analysis was performed on the surgical treatment of 63 patients with thymoma and MG. Results The complete resection of the surgery in 52 cases (82.5%), no operative death. At 5 years after operation, the 10-year survival rates were 69.4% and 516% respectively, 79.4% and 58.3% for non-invasive thymoma group and 46.7% and 266% for invasive group respectively %, Stage I and stage II were 76.9% and 57.8% respectively, with stage III and stage IV being 40% and 200% respectively. Conclusion The prognosis of thymoma combined with MG is closely related to the clinical stage, histological classification and completeness of surgical resection. The perioperative management and Osserman classification also affect the surgical outcome and prognosis