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目的分析奥美拉唑与西咪替丁治疗应激性胃溃疡的效果。方法选取102例应激性胃溃疡患者为研究对象,在取得患者同意的基础上,将患者随机均分为对照组(予以西咪替丁治疗)和观察组(予以奥美拉唑治疗),各51例,比较两组药物的治疗效果。结果 1观察组患者的止血时间、血清胃激素水平均优于对照组,两组差异显著(P<0.05);2观察组患者的治疗总有效率为92.16%(47/51),对照组为76.47%(39/51),两组差异显著(P<0.05)。结论在应激性胃溃疡的治疗中,与西咪替丁相比,奥美拉唑的效果更佳,值得临床推广。
Objective To analyze the effect of omeprazole and cimetidine in the treatment of stress ulcer. Methods A total of 102 stress ulcer patients were selected as study subjects. On the basis of consent of patients, the patients were randomly divided into control group (treated with cimetidine) and observation group (treated with omeprazole) 51 cases in each group, comparing the therapeutic effect of two groups of drugs. Results 1 The observation group had better hemostatic time and serum levels of serum hormone than the control group, with significant difference between the two groups (P <0.05). The total effective rate of the observation group was 92.16% (47/51) 76.47% (39/51), the difference between the two groups was significant (P <0.05). Conclusion Omeprazole is more effective than cimetidine in the treatment of stress ulcer, which is worthy of clinical promotion.