当前广泛应用的胚胎评估手段主要是依靠形态学分析,有主观性和难以标准化的缺点,其效能也存有争议。近年发展的一些新的侵入性(如基因组、转录组、蛋白质组等)和非侵入性(如新形态学、氧代谢、代谢组学等)的胚胎发育潜能评估手段中,部分方法已显现出广阔的临床应用前景。本文就这些新的技术手段做一综述,以期为临床和科研工作带来提示。 Currently widely used methods of embryo evaluation rely mainly on morphological analysis, subjectivity and the difficulty of standardization, its effectiveness is also controversial. In recent years, some new invasive methods (such as genomics, transcriptome, proteomics, etc.) and noninvasive (such as new morphology, oxygen metabolism, metabolomics, etc.) Broad clinical application prospects. This article reviews these new technologies in order to provide hints for clinical and scientific research.