采用１∶２配比的病例对照研究方法，调查哈市１９８９年以来发病的３４例儿童ＩＤＤＭ病例，６８例对照。经单因素分析：易患感冒、原因不明发热、胃肠道感染、腮腺炎、呼吸道感染、手术外伤史、精神压力、孕母发热、糖尿病家族史均能增加发病风险。经条件Ｌｏｇｉｓｔｉｃ回归模型多因素分析，筛选出易感冒、呼吸道感染、胃肠道感染、原因不明发热为引起ＩＤＤＭ发病的主要危险因素。 A case-control study with a ratio of 1: 2 was used to investigate 34 IDDM cases and 68 controls in Harbin since 1989. Univariate analysis showed that susceptible to the flu, unexplained fever, gastrointestinal tract infection, mumps, respiratory tract infection, history of surgical trauma, stress, maternal fever and family history of diabetes all increased the risk of onset. Logistic regression model by conditional multivariate analysis, screening for susceptible to influenza, respiratory infections, gastrointestinal infections, unexplained fever is the main risk factor for IDDM.