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目的:观察丙泊酚复合芬太尼用于人工流产术的效果。方法:选择120例人工流产术患者ASAⅠ级～Ⅱ级,于手术区消毒时静注芬太尼0.75μg/kg～1μg/kg,丙泊酚2mg/kg～2.5mg/kg,待患者意识消失后开始手术,在扩张宫颈和吸宫时有肢体扭动追加丙泊酚20mg～40mg以维持适当的麻醉深度。记录术前、术中和术后的SBP、DBP、HR、SPO2的变化;记录术中丙泊酚用量和停药后患者苏醒时间;观察术中呼吸抑制、肢体扭动、术后恶心呕吐和腹部疼痛情况。结果:患者的SBP、DBP、HR术前与术后无显著差异,术中显著低于术前和术后(P<0.05),麻醉期间SPO2无明显变化。丙泊酚平均用量(115±20)mg,苏醒时间为8min～12min。无明显呼吸抑制和恶心呕吐等不良反应发生。结论:丙泊酚复合芬太尼用于人工流产术麻醉效果确切,丙泊酚用量减少,呼吸抑制和恶心呕吐发生率低,且不延长苏醒时间,是比较理想的配伍方法,值得临床推广应用。
Objective: To observe the effect of propofol combined with fentanyl in artificial abortion. Methods: A total of 120 ASA grade Ⅰ ~ Ⅱ patients were selected. Intravenous fentanyl of 0.75 μg / kg ~ 1 μg / kg and propofol of 2 mg / kg ~ 2.5 mg / kg were administered intravenously when the operation area was disinfected. After surgery, in the expansion of the cervix and suction when the limbs writhing additional propofol 20mg ~ 40mg to maintain proper depth of anesthesia. The changes of SBP, DBP, HR and SPO2 were recorded before, during and after operation. The dosage of propofol and the recovery time of patients after stopping were recorded. The intraoperative respiratory depression, limb writhing, postoperative nausea and vomiting Abdominal pain situation. Results: There was no significant difference in preoperative and postoperative SBP, DBP and HR between the two groups. The postoperative and postoperative levels of SBP, DBP and HR were significantly lower than those before and after operation (P <0.05). There was no significant change in SPO2 during anesthesia. The average propofol dosage (115 ± 20) mg, awake time of 8min ~ 12min. No obvious respiratory depression and nausea and vomiting and other adverse reactions. Conclusion: Propofol combined with fentanyl for abortion is effective in anesthesia, propofol dosage reduction, respiratory depression and nausea and vomiting, and does not prolong the recovery time is an ideal method of compatibility, it is worthy of clinical application .