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目的:探讨妊娠晚期妇女凝血及纤溶系统的改变与临床意义。方法:选取180例妊娠晚期(平均孕周37.5周)妇女,检测其血浆中凝血酶原时间(PT),活化全血凝固时间(APTT),纤维蛋白(FIB),D-二聚体(D-Dimer)等4项指标。选取健康非妊娠妇女45例作为对照。结果:妊娠晚期妇女血浆PT,APTT,FIB,D-Dimer值与对照组比较差异均有统计学意义(P<0.05)。结论:妊娠晚期妇女血液处于高凝状态,检测上述4项指标,对防止妊娠晚期血栓形成、妊娠高血压综合征等并发症有一定临床意义。
Objective: To investigate the changes and clinical significance of coagulation and fibrinolytic system in the third trimester of pregnancy. Methods: One hundred and eighty pregnant women (average gestational age 37.5 weeks) were enrolled in this study. Prothrombin time (PT), APTT, fibrin (FIB) and D-dimer -Dimer) and other four indicators. Select healthy non-pregnant women, 45 cases as a control. Results: The plasma levels of PT, APTT, FIB and D-Dimer in third trimester women were significantly different from those in control group (P <0.05). Conclusion: The blood of pregnant women in hypercoagulable state, the detection of the above four indicators, to prevent late pregnancy thrombosis, complications such as pregnancy-induced hypertension has some clinical significance.