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目的:探究临床治疗胃溃疡患者的过程中,评价应用兰索拉唑的治疗效果及对多种血浆因子表达水平的影响。方法:自我院2015年5月-2016年6月期间收治的128例胃溃疡患者,对比患者应用不同治疗方案进行治疗,观察临床疗效及多种血浆因子的表达水平。结果:予以不同治疗方案后,对试验组患者采用兰索拉唑治疗的各项血浆因子的表达水平均明显优于对照组,如MDA、SOD、NO等,差异显著(P<0.05)。对试验组患者采用兰索拉唑治疗的临床总有效率(92.2%,59/64)显著高于对照组(75.0%,48/64),差异显著(P<0.01)。结论:临床治疗胃溃疡患者的过程中,兰索拉唑可显著提升治疗效果并改善多种血浆因子的表达水平,应广泛推广。
Objective: To investigate the clinical treatment of patients with gastric ulcer in the evaluation of the application of lansoprazole treatment and the impact of a variety of plasma factor expression levels. Methods: A total of 128 patients with gastric ulcer admitted to our hospital from May 2015 to June 2016 were enrolled in this study. Patients in the control group were treated with different treatment regimens, and the clinical efficacy and the expression of various plasma factors were observed. Results: After different treatment regimens, the plasma levels of all the plasma factors treated with lansoprazole in the experimental group were significantly higher than those in the control group, such as MDA, SOD and NO (P <0.05). The total effective rate (92.2%, 59/64) of the patients treated with lansoprazole was significantly higher than that of the control group (75.0%, 48/64) (P <0.01). Conclusions: Lansoprazole can significantly improve the therapeutic effect and improve the expression of various plasma factors during the clinical treatment of patients with gastric ulcer, which should be widely promoted.