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急性白血病(AL)患者特别易患侵袭性肺曲霉病(invasive pulmonary aspergillosis,IPA)。本文通过观察15例经病理学证实为IPA的急性白血病患者的临床经过,并同时以45例急性白血病患者的临床经过作为对照组进行研究,以鉴定AL患IPA的主要危险因素。 70例 AL患者系1978年7月～1981年1月在宾夕法尼亚大学医院肿瘤研究机构接受治疗的住院病人。病例组(15例)和对照组(45例)入院前患IPA的各种危险因素包括肺病史、副鼻窦病史、化疗方案、吸烟史、白血病复发次数等均相似,经统计学处理其差别均无显著性。为了进一步摒除病例组与对照
Patients with acute leukemia (AL) are particularly susceptible to invasive pulmonary aspergillosis (IPA). In this paper, by clinical observation of 15 cases of pathologically confirmed acute leukemia in patients with clinical and at the same time 45 cases of acute leukemia in patients with clinical trials as a control group to identify the main risk factors for IPA AL. Seventy patients with AL were hospitalized at the University of Pennsylvania Hospital Cancer Institute from July 1978 to January 1981. In the case group (15 cases) and the control group (45 cases), the various risk factors of IPA before admission were lung disease history, paranasal sinus disease history, chemotherapy regimen, smoking history and leukemia recurrence frequency. All the differences were statistically analyzed No significant. In order to further exclude the case group and control