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目的分析肺泡灌洗液培养细菌菌株种类变化和药敏结果 ,为治疗社区获得性肺炎(CAP)提供病原学依据。方法符合CAP诊断标准,综合肺泡灌洗液培养阳性病例,统计分析细菌种类及药敏结果。结果培养细菌共计186例,其中革兰阴性杆菌共128例,占68.8%;革兰阳性球菌共计58例,占31.1%;肺炎支原体共计12例,占6.3%。结论重症CAP感染的病原菌以革兰阴性杆菌为主,在前四位的分别是大肠埃希菌、流感嗜血杆菌、枸橼酸杆菌、肺炎克雷伯杆菌。大部分对头孢哌酮舒巴坦针敏感。结论本院重症CAP感染的细菌以革兰阴性杆菌为主,对舒普深敏感性高,临床治疗效果好。
Objective To analyze the changes of bacterial strains and drug susceptibility in cultured bronchoalveolar lavage fluid and provide etiological evidence for the treatment of community-acquired pneumonia (CAP). Methods According to CAP diagnostic criteria, the positive cases of bronchoalveolar lavage fluid culture were collected, and the bacterial species and drug susceptibility results were statistically analyzed. Results A total of 186 bacteria were cultured, of which 128 were Gram-negative bacilli (68.8%), 58 were Gram-positive cocci (31.1%), and 12 were Mycoplasma pneumoniae (6.3%). Conclusions Gram-negative bacilli are the main pathogenic bacteria in severe CAP infection. The top four strains are Escherichia coli, Haemophilus influenzae, Citrobacter, and Klebsiella pneumoniae respectively. Most are sensitive to cefoperazone sulbactam. Conclusions Severe CAP-infected bacteria in our hospital are Gram-negative bacilli, which have a high sensitivity to schneider and good clinical curative effect.