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目的:剖析急性冠脉综合征应用替格瑞洛对患者血小板聚集功能及心肌灌注的影响作用.方法:86例急性冠脉综合征患者以随机抽签法分为对照组、观察组,每组43例.对照组予以阿司匹林与氯吡格雷进行抗血小板治疗,观察组予以阿司匹林与替格瑞洛进行抗血小板治疗.统计并比较两组病患在血小板计数、血小板聚集率及心肌肌钙蛋白方面的指标差异.对比两组病患的心肌灌注相关指标.结果:观察组治疗后的血小板计数及聚集率低于对照组,且心肌肌钙蛋白也较低,与对照组差异明显(P＜0.05);观察组治疗后的心肌灌注相关指标优于对照组,差异明显(P“,”Objective: to analyze the effects of tegranolol on platelet aggregation and myocardial perfusion in patients with acute coronary syndrome. Methods: 86 patients with acute coronary syndrome were randomly divided into control group and observation group, with 43 cases in each group. The control group was treated with aspirin and clopidogrel, and the observation group was treated with aspirin and tigritol. The differences of platelet count, platelet aggregation rate and cardiac troponin between the two groups were counted and compared. Myocardial perfusion related indexes were compared between the two groups. Results: the platelet count and aggregation rate of the observation group were lower than those of the control group, and the cardiac troponin was also lower, which was significantly diiferent from that of the control group ( P ＜ 0. 05 ); The indexes related to myocardial perfusion in the observation group were better than those in the control group ( P ＜ 0. 05 ) . Conclusion: in the treatment ofpatientswithacutecoronarysyndrome, tegranololcansignificantlyinhibitplateletaggregation, protectmyocardialfunctionandreducereperfu-sion injury. It is worthy of clinical application.