本文对原发性肝癌、良性肝病和健康人血清唾液酸的研究表明 ,原发性肝癌患者血清唾液酸水平明显增高(6 36 .7± 76 .6 ug/ ml) ,与良性肝病及健康人相比有显著性差异 (P<0 .0 1)。血清唾液酸对原发性肝癌的诊断敏感度为70 % ,特异性为 88.3% ,阳性预示值为 75 .0 % ,阴性预示值为 85 .5 % ,准确性为 82 .2 %。据此认为 ,血清唾液酸是原发性肝癌诊断和鉴别诊断较好的标记物之一 This study of primary liver cancer, benign liver disease and healthy human serum sialic acid showed that patients with primary liver cancer serum sialic acid levels were significantly higher (36.67 ± 76.6 ug / ml), and benign liver disease and healthy people There was significant difference (P <0.01). Serum sialic acid had a sensitivity of 70%, a specificity of 88.3%, a positive predictive value of 75.0%, a negative predictive value of 85.5% and an accuracy of 82.2%. Accordingly, serum sialic acid is one of the better markers for the diagnosis and differential diagnosis of primary liver cancer