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目的评价沙丁胺醇与硫酸镁联合雾化吸入治疗支气管哮喘的临床效果。方法选取科右前旗人民医院2013年3月到2015年3月门诊确认的100名支气管哮喘的患者为研究对象,按照随机以及结合患者意愿的方法分为观察组与对照组。两组患者在年龄、性别、病情等方面差异无统计学意义。对照组给予沙丁胺醇雾化吸入治疗,观察组给予沙丁胺醇与硫酸镁联合雾化吸入治疗。通过检测患者的肺功能恢复情况,第一秒用力呼气量(FEV1)、最大呼气流量(PEF),评价此种方法的临床效果以及安全性。结果两组患者在治疗后,FEV1与PEF相对比激发值均有提高(P<0.05);观察组的患者的FEV1与PEF的上升率高于对照组(P<0.05),且恢复后的FEV1与PEF值高于对照组。在20 min后,患者的肺功能值恢复至正常值。在观察组中出现1(2%)例副作用的患者。结论沙丁胺醇与硫酸镁雾化吸入对于支气管哮喘的治疗有积极的临床治疗效果,但是对于进一步的使用,需要进行更深的研究与探索,减少其对患者的副作用。
Objective To evaluate the clinical efficacy of salbutamol combined with magnesium sulfate in the treatment of bronchial asthma. Methods A total of 100 patients with bronchial asthma confirmed by the People’s Hospital of Kezuoqianqi from March 2013 to March 2015 were selected as study subjects and divided into observation group and control group randomly and in combination with patients’ wishes. Two groups of patients in terms of age, gender, illness and other differences were not statistically significant. The control group was given albuterol inhalation therapy, and the observation group was given salbutamol and magnesium sulfate combined with inhalation therapy. The clinical efficacy and safety of this method were evaluated by examining the patient’s pulmonary function recovery, FEV 1 and PEF. Results After treatment, the FEV1 and PEF stimulated values were significantly increased (P <0.05). The rising rate of FEV1 and PEF in the observation group was higher than that of the control group (P <0.05), and the FEV1 With PEF value higher than the control group. After 20 minutes, the patient’s lung function returned to normal. One (2%) cases of side effects occurred in the observation group. Conclusion Salbutamol and magnesium sulfate inhalation have a positive clinical effect on the treatment of bronchial asthma. However, for further use, further research and exploration are needed to reduce their side effects on patients.