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咽部神经鞘膜瘤在临床上比较少见,本文报道8例,此瘤又名雪旺氏瘤,来源于神经鞘膜的雪旺氏细胞,发生原因不明。多发生于四肢,在头颈可发生于听神经、面神经、眼、耳、鼻、舌、硬腭、口腔及唾液腺等处。好发年龄为20~40岁,性别发生率大致相等。显微镜检查:雪旺氏细胞为主要细胞,梭形细胞排列致密,有长椭圆细胞核,其长轴互相平行呈栅栏状排列。常见的症状有咽异物感,吞咽障碍,发音改变,甚至呼吸困难等。当肿瘤压迫咽部、颈部的神经,可产生相应的神经症状。肯定的诊断应靠病理学检查确定。治疗以手术摘除为主。本肿瘤属良性,故手术后很少复发,预后良好。
Pharyngeal nerve sheath tumors are relatively rare in the clinic, this article reported 8 cases, this tumor is also known as Schwann’s tumor, Schwann cells from the nerve sheath, the cause is unknown. Occurs in the limbs, in the head and neck can occur in the auditory nerve, facial nerve, eyes, ears, nose, tongue, hard palate, mouth and salivary glands. The prevalent age is 20 to 40 years old, and the incidence of gender is roughly equal. Microscopic examination: Schwann cells were the main cells. The spindle cells were arranged densely and had long elliptic nuclei. Their long axes paralleled each other in a palisade arrangement. Common symptoms include pharyngeal foreign body sensation, dysphagia, altered pronunciation, and even breathing difficulties. When the tumor compresses the nerves of the pharynx and neck, it can produce corresponding neurological symptoms. A positive diagnosis should be determined by pathological examination. The main treatment is surgical removal. The tumor is benign, so it rarely recurs after surgery and has a good prognosis.