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本文报道了德州地区1973～1979年流行性脑脊髓膜炎(流脑)周期流行中人群脑膜炎奈瑟氏菌感染的菌群和血清抗体的调查资料。作者指出,当前流脑的流行菌株95%以上是A群流脑菌,带菌菌株是以B群占绝对优势。健康带菌具有带菌率高、带菌期长和相对稳定等特点。作者认为,总带菌率与流脑流行无关,而A群带菌率却与流脑的流行趋势基本一致。人群血凝抗体的调查资料表明,流脑多发生于A群血凝抗体基础水平较低的人群中,发病高峰是由于人群对流行菌株普遍易感所致。带菌感染所产生的交叉免疫反应,有防止流脑发病的重要作用。
This article reports the investigation of the bacterial population and serum antibody to Neisseria meningitidis infection in the cyclical epidemic of meningococcal meningitis from 1973 to 1979 in Texas. The author points out that currently more than 95% of the epidemic strains of meningitis are group A meningitidis, and the group B is absolutely dominant. Healthy carrier with a carrier rate, long period and relatively stable characteristics. The author believes that the total carrier rate has nothing to do with the epidemic of meningitis, while the group A carrier rate but consistent with the popular trend of meningitis. The survey data of the hemagglutinating antibodies in the population show that the meningitis mostly occurs in the population with a lower basic level of hemagglutination antibody in group A, and the peak incidence is due to the general susceptibility of the crowd to the epidemic strains. Crossed immune response generated by infection, there is an important role in preventing the incidence of meningitis.