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对我国新疆等11个省、自治区分离的418株鼠疫菌进行糖醇(鼠李糖、甘油、蜜二糖、松三糖、阿胶糖和麦芽糖)酵解、脱氮,营养型、聚丙烯酰胺凝胶电泳蛋白分析,Pgm~+细胞突变为 Pgm~-速率、内毒素含量、FI 抗原含量、Pst Ⅰ产生及对 Pst Ⅰ敏感性的差异以及在离体人血清中生长速率等项指标的研究,可将我国鼠疫菌分成17个生态型。17个型鼠疫菌均各有特定的地理位置。对人的侵袭力,致病性亦各有不同。以青藏高原型、冈底斯山型(主要宿主为喜马拉雅旱獭)对人的侵袭力和致病性最强,而锡林格勒高原型(主要宿主为布氏田鼠)则最弱。作者建议鼠疫菌分型的命名以生态型较为适宜。
A total of 418 strains of Yersinia pestis isolates from 11 provinces and autonomous regions in China such as glycolysis (rhamnose, glycerol, melibiose, melezitose, gelatin and maltose) were digested, denitrified, nutritious, polyacrylamide Analysis of gel electrophoretic proteins, Pgm ~ + mutation to Pgm ~ - rate, endotoxin content, FI antigen content, Pst Ⅰ production, Pst Ⅰ sensitivity, and growth rate in isolated human serum , We can divide our plague bacteria into 17 ecotypes. 17 types of plague bacteria have their own specific geographical location. On human invasiveness, pathogenicity is also different. The invasiveness and pathogenicity of the Qinghai-Tibet Plateau and the Gangdese Mountain (mainly Himalayan marmot) are the strongest in humans, while the Xilinge Plateau (the main host is Brandt’s vole) is the weakest. The authors suggest that the naming of Y. pestis species should be more eco-friendly.