论文部分内容阅读
目的检测CoaguChek XS快速凝血分析仪测量国际标准化比值(INR)的准确性、相关性及一致性。方法在40例患者服用华法林前l天、服药后第5天、第7天,同时使用标准实验室及快速凝血分析仪检测INR。结果标准实验室及快速凝血分析仪检测的INR接近,差异无统计学意义(P>0.05)。两种检测方法测定的INR呈正相关,且相关程度强(r=0.876,P<0.01),具有较好的一致性。老年患者亚组分析结果与总人群分析结果一致。结论 CoaguChek XS快速凝血分析仪测定的INR准确性高,与标准实验室检测的INR有良好的相关性和一致性。快速凝血分析仪可以用于口服华法林患者,包括老年患者。
Objective To examine the accuracy, relevance and consistency of the International Standardization Ratio (INR) for the CoaguChek XS Fast Coagulation Analyzer. Methods Forty patients were treated with warfarin for one day, five days and seven days after taking the medicine. Meanwhile, INR was measured by standard laboratory and rapid coagulation analyzer. Results There was no significant difference in INR between standard laboratory and rapid coagulation analyzer (P> 0.05). The INRs measured by the two tests were positively correlated and correlated strongly (r = 0.876, P <0.01) with good agreement. Analysis of subgroups of elderly patients with the total population analysis results. Conclusions The INR of the CoaguChek XS Fast Coagulation Analyzer is highly accurate and has good correlation and agreement with INR in standard laboratory tests. Rapid coagulation analyzer can be used for oral warfarin patients, including elderly patients.