患者,女,60岁,4年前冷水浴后全身出现米粒大痒疹,诊为“湿疹“,抗过敏无效,渐变为斑片。活检诊为“神经性皮炎”,1980年8月于左肩胛内缘及下缘之斑片上各出现一拇指甲大,凸起皮肤的半球形淡红结节,两次病检,为“蕈样霉菌病”与“蕈样肉芽肿”。同年11月上旬开始体温波动在37.5℃～39℃。12月6日于门诊开始静脉注射环膦酰胺,至入院时共3.4克,搔痒明显减轻。入院后体检:体温38.4℃。全 Patient, female, 60 years old, 4 years after the cold water body appeared whole body prurigo rice, diagnosed as “eczema”, anti-allergy ineffective, gradually changed to patch. Biopsy diagnosis of “neurodermatitis”, in August 1980 on the left shoulder blade and the lower edge of the patch on each appear a thumbnail large, protruding hemispherical pink nodules of the skin, twice diseased, as “mushroom Like mycosis ”and“ Mycosis fungoides. ” The same year in early November body temperature fluctuations in the 37.5 ℃ ~ 39 ℃. December 6 intravenous injection of cyclophosphamide in the clinic, to a total of 3.4 grams at admission, itching significantly reduced. Physical examination after admission: body temperature 38.4 ℃. all