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目的:通过对彗星试验(又称单细胞凝胶电泳试验)检测致癌物的敏感性、检测谱、遗传毒性检出阈(检出阳性反应的最低剂量)的初步评价,为其在化学致癌性检测和环境致癌的生物监测中的应用提供依据。方法:选择11类37种已知致癌性化合物,利用彗星试验以悬浮暴露方式检测
OBJECTIVE: To evaluate the sensitivity of detection of carcinogens, detection spectrum and detection threshold of genotoxicity (the lowest dose for detecting positive reaction) in comet assay (also known as single cell gel electrophoresis test) Detection and environmental carcinogens in the biological monitoring of the application provided. Methods: Eleven 37 known carcinogenic compounds were selected and tested by comet assay in suspension exposure