在近二年内,我们曾遇到了9例经应用抗疟药物后发生明显的毒性反应,其中2例极为严重,几乎危及生命。兹将该9例作一简要报导,并复习有关文献,以供参考。一、乙氨嘧啶引起昏迷一例: 住院号77836,女性,2岁。患者于1961年11月4日起有间歇性高热,5天后被当地诊所诊断为瘧疾,给口服乙氨嘧啶,自当日上午八时起在5小时半的时间内共服乙氨嘧啶三次,总 In the past two years, we have encountered nine significant toxic reactions after the application of anti-malarial drugs, two of which were extremely serious and almost life-threatening. The 9 cases will be a brief report, and review the literature for reference. A, caused by comatidine A case: hospital number 77836, female, 2 years old. The patient developed intermittent hyperthermia on November 4, 1961, and was diagnosed with malaria five days later by a local clinic. He was given oral pyrimethamine and served three doses of pyrimethamine three times within 5 and a half hours from 8 am