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利用活性炭的缓释性和肿瘤、淋巴系统的高亲合性,以活性炭吸附抗癌药物来延长药物在局部的作用.作者将活性炭用于小鼠和人胃,对摘除淋巴结进行大体及镜下检查,观察活性炭微粒在淋巴结内的移行与分布.结果示,在小鼠淋巴结大体及镜下黑染率均为100%;人胃淋巴结大体黑染率为85.14%,镜下为100%.镜下见活性炭微粒沿毛细淋巴管移行,并与癌细胞一并移行于淋巴窦内,附于癌细胞的表面.
Using active carbon’s sustained-release properties and high affinity of tumor and lymphatic system, active carbon adsorption of anti-cancer drugs is used to prolong the local effect of the drug. The authors used activated charcoal for mice and human stomach and performed gross and microscopic removal of lymph nodes. Examinations were conducted to observe the migration and distribution of activated carbon particles in lymph nodes. The results showed that both the gross and microscopic black staining rates of mouse lymph nodes were 100%; the gross black staining rate of human gastric lymph nodes was 85.14%, and the microscope was 100%. Next, the activated carbon particles migrate along the lymphatic capillaries and migrate along with the cancer cells in the lymphatic sinus and attach to the surface of the cancer cells.