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目的:探讨环磷酰胺冲击治疗风湿免疫疾病的临床效果。方法:以我院收治的82例类风湿关节炎患者为研究对象,采用对比研究的方式,将其根据治疗方式不同分为对照组与观察组,对照组给予甲氨蝶呤治疗,观察组给予环磷酰胺治疗,观察两组患者的治疗效果及不良反应发生情况。结果:观察组临床症状改善情况明显优于对照组,p<0.05;且观察组ESR、CRP的变化情况也优于对照组,差异显著(p<0.05)。结论:环磷酰胺冲击治疗风湿免疫疾病的临床效果显著,能有效改善患者的临床症状及体征,值得临床推广。
Objective: To investigate the clinical effect of cyclophosphamide in the treatment of rheumatic immune disease. Methods: Eighty-two patients with rheumatoid arthritis admitted to our hospital were enrolled in this study. The patients were divided into control group and observation group according to different treatment methods. The control group was treated with methotrexate and the observation group was given Cyclophosphamide treatment, the treatment of two groups were observed and the incidence of adverse reactions. Results: The improvement of clinical symptoms in the observation group was significantly better than that in the control group, p <0.05; and the changes of ESR and CRP in the observation group were also better than those in the control group (p <0.05). Conclusion: The clinical effect of cyclophosphamide in the treatment of rheumatic immune disease is significant, which can effectively improve the clinical symptoms and signs of patients and is worthy of clinical promotion.