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为了研究幽门螺杆菌(HelicobacterPylori,Hp)相关性十二指肠溃疡的治疗方法,将本病496例随机分为六组。A组奥美拉唑40mg,每天1次,治疗2周。B组:泰胃美800mg,每晚1次,治疗4周。C组:胶体铋剂(德诺)120mg,每天4次,治疗4周、弗莱莫星500mg,每天4次治疗2周。D组:奥美拉唑40mg,每天1次,弗莱莫星250mg和甲硝唑200mg各每日4次,治疗2周。E组:泰胃美800mg,每晚1次,治疗4周,弗莱莫星250mg和甲硝唑200mg,每日4次,治疗2周。F组:胶体铋剂(德诺)120mg,每天4次治疗4周,弗莱莫星250mg和甲硝唑200mg各每日4次,治疗2周。疗程结束4周后用快速尿素酶试验和Warthin-Stary银染法复查Hp,两项均阳性者定为有Hp感染,两项均阴性时判断Hp已被根除。结果显示A,B,C,D,E,F组溃疡愈合率分别为82.7%、68.5%、79.3%、88.5%、80.4%和79.2%。Hp根除率分别为40.7%、9.5%、75.6%、87.5%、71.3%和83.3%。溃疡愈合率D,E,F三组之间比较或D,E,F与C组比较或A组与D,E,F,C组比?
In order to study the treatment of Helicobacter pylori (Hp) -related duodenal ulcer, 496 patients were randomly divided into six groups. Group A omeprazole 40mg, 1 day, for 2 weeks. Group B: Thai Weimei 800mg, 1 night, for 4 weeks. Group C: colloidal bismuth (Deno) 120mg, 4 times a day, for 4 weeks, 500mg of Fleimotoxin, 4 times a day for 2 weeks. Group D: omeprazole 40mg, once daily, 250mg mefenamicin and 200mg metronidazole 4 times daily for 2 weeks. Group E: Thai Weimei 800mg, 1 night, treatment for 4 weeks, 250mg meridian and metronidazole 200mg, 4 times a day for 2 weeks. Group F: colloidal bismuth (Deno) 120mg, 4 times a day for 4 weeks, 250mg mefenamicin and metronidazole 200mg 4 times a day for 2 weeks. Four weeks later, Hp was examined by rapid urease assay and Warthin-Stary silver staining. Both were positive for Hp infection and both were negative for Hp being eradicated. The results showed that the healing rates of ulcer in groups A, B, C, D, E and F were 82.7%, 68.5%, 79.3%, 88.5%, 80.4% and 79.2%, respectively. Hp eradication rates were 40.7%, 9.5%, 75.6%, 87.5%, 71.3% and 83.3%, respectively. Ulcer healing rate D, E, F comparison between the three groups or D, E, F and C group or group A and D, E, F, C group?