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目的 探讨糖尿病患者不自觉低血糖(UH)发作的相关因素。方法 对36 例UH 和30 例自觉低血糖(AH)的有关资料进行统计学分析。结果 UH 组低血糖发作次数、既往低血糖发作史、肾脏病变和自主神经病变发生率明显高于AH 组。UH 发作与上述指标呈正相关。UH组糖化血红蛋白的水平低于AH 组,UH 发作与糖化血红蛋白呈负性相关。Logistic 多因素回归分析,在调整既往低血糖史等诸影响因素后,低血糖发作次数与UH 发生呈显著正相关(OR=3-97 ,95 % CI为1-72 ~9-16 ,P= 0-002)。结论 低血糖反复发作是UH 发生的独立危险因素
Objective To investigate the related factors of unconscious hypoglycemia (UH) attack in diabetic patients. Methods The data of 36 patients with UH and 30 patients with conscious hypoglycemia (AH) were statistically analyzed. Results The frequency of hypoglycemic episodes, previous episodes of hypoglycemia, nephropathy and autonomic neuropathy in the UH group were significantly higher than those in the AH group. UH seizures and the above indicators was positively correlated. The level of glycosylated hemoglobin in group UH was lower than that in group AH, and the occurrence of UH was negatively correlated with glycosylated hemoglobin. Logistic regression analysis showed that there was a significant positive correlation between the frequency of hypoglycemic episodes and the occurrence of UH (OR = 3-97, 95% CI 1-72-9-16, P = 0-002). Conclusions Hypoglycemia recurrent episodes are independent risk factors for the occurrence of UH