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目的探讨新生儿呼吸机相关性肺炎(VAP)的临床及病原菌特点。方法分析2007年12月—2010年12月发生呼吸机相关性肺炎的50例新生儿的病原菌谱及耐药性。结果 50例呼吸机相关性肺炎患儿中23例分泌物培养阳性,阳性率46%,培养出病原菌28株。其中G-杆菌阳性21株(占75%),G+球菌阳性6株(占21.42%),合并真菌感染(假丝酵母菌)1例。结论早产儿呼吸机相关性肺炎(VAP)的发生与多因素有关,对早产儿VAP应采取综合措施进行防治。
Objective To investigate the clinical and pathogenic characteristics of neonatal ventilator-associated pneumonia (VAP). Methods The pathogenic bacteria spectrum and drug resistance of 50 neonates with ventilator-associated pneumonia who developed from December 2007 to December 2010 were analyzed. Results Of the 50 cases of respiratory-related pneumonia in children, 23 cases were positive for secretions, with a positive rate of 46% and 28 pathogens were cultivated. Among them, 21 (75%) were positive for G-bacilli and 6 (21.42%) were positive for G-coccus, and 1 was complicated by fungal infection (Candida). Conclusions The occurrence of ventilator-associated pneumonia (VAP) in preterm infants is related to many factors. Comprehensive measures should be taken to prevent and treat VAP in premature infants.