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目的分析2013-2014年安康市手足口病的病原学特征,为该病预防提供依据。方法对安康市10个区、县送检的手足口病(HFMD)患者临床标本采用实时荧光定量PCR方法进行检测。结果共检测标本1 113份,其中489份肠道通用型病毒核酸阳性,检出率为43.94%;EV71阳性率为31.90%(156/489),Cox Al6阳性率为23.72%(116/489);其他肠道病毒阳性为44.38%(217/489)。不同性别间阳性检出率差异有统计学意义(χ2=6.62,P<0.05),5岁以下儿童为高发人群。结论 2013年和2014年HFMD主要流行病原均为其他肠道病毒,应加强手足口病病原监测,并对其他肠道病毒的进一步分型检测。
Objective To analyze the etiological characteristics of HFMD in Ankang City from 2013 to 2014 and provide evidence for its prevention. Methods The clinical specimens of hand, foot and mouth disease (HFMD) patients in 10 districts and counties in Ankang City were detected by real-time fluorescence quantitative PCR. Results A total of 1 113 samples were detected, of which 489 were positive for enterovirus, the detection rate was 43.94%; the positive rate of EV71 was 31.90% (156/489); the positive rate of Cox Al6 was 23.72% (116/489) ; Other enterovirus positive was 44.38% (217/489). There was significant difference in the positive detection rate among different sexes (χ2 = 6.62, P <0.05), while children under 5 years old were high incidence population. Conclusions The major epidemic pathogens of HFMD in 2013 and 2014 are all other enteroviruses. Pathogen surveillance of HFMD should be strengthened and further typing of other enteroviruses detected.