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目的:分析抗凝治疗在恶性肿瘤前血栓状态(PTS)中的临床应用价值。方法:选取江门市中心医院2014年10月至2016年12月共100例恶性肿瘤合并PTS患者,采用随机分配的方式,分为观察组和对照组各50例。观察组给予抗凝治疗,对照组未给予抗凝治疗,对比两组患者的临床疗效。结果:观察组患者静脉血栓发生率低于对照组,差异具有统计学意义(P<0.05)。观察组中有部分患者在治疗过程中出现相关急性胃黏膜病变,未出现严重的并发症。结论:抗凝治疗对恶性肿瘤合并PTS患者具有一定的临床疗效,能有效降低静脉血栓的发生率,保证患者的生活质量,促进患者的康复。
Objective: To analyze the clinical value of anticoagulant therapy in pre-malignant thrombosis (PTS). Methods: A total of 100 patients with malignant tumor complicated with PTS from October 2014 to December 2016 in Jiangmen Central Hospital were enrolled. Fifty patients were randomly divided into observation group and control group. The observation group was given anticoagulant therapy, the control group was not given anticoagulant therapy, compared the clinical efficacy of two groups of patients. Results: The incidence of venous thrombosis in observation group was lower than that in control group, the difference was statistically significant (P <0.05). Some patients in the observation group during the course of treatment related to acute gastric mucosal lesions, no serious complications. Conclusion: Anticoagulant therapy has certain clinical effect on patients with malignant tumor complicated with PTS, can effectively reduce the incidence of venous thrombosis, ensure the quality of life of patients and promote the recovery of patients.