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目的观察急性心肌梗死 (AMI)溶栓后血管再通和未通者与未溶栓者血清肌钙蛋白的动态变化。方法定量测定 93例 AMI患者的心肌肌钙蛋白 I(c Tn I) ,以 >10 0 ng/ L作为阳性判定值。结果溶栓再通者 c Tn I峰值较未通组与未溶栓组显著增高 (P<0 .0 5 ) ,且峰值增大 ,峰值时间提前 8小时 ,再通组 c Tn I恢复正常时间平均为 (13 0± 3 8)小时 ,较未通者提前 60小时。结论溶栓后动态测定血清c Tn I浓度、峰值时间 ,可作为判断溶栓成功的指标之一。
Objective To observe the dynamic changes of serum troponin in patients with recanalization and non-thrombolysis after acute myocardial infarction (AMI) thrombolysis. Methods The cardiac troponin I (cTn I) levels of 93 patients with AMI were measured quantitatively with> 10 0 ng / L as the positive predictive value. Results The peak value of cTn I in thrombolytic recanalization was significantly higher than that in non-thrombolytic group (P <0.05), and the peak value was increased. The peak time was 8 hours earlier, and the recanalization group cTn I returned to normal time With an average of (13 0 ± 3 8) hours, 60 hours earlier than those without. Conclusion The dynamic determination of serum cTn I concentration and peak time after thrombolysis can be used as one of the indexes to judge the success of thrombolysis.