通常认为乙肝患者血清中HBeAg存在表示肝脏病变活动性及损害较严重。当HBeAg消失,抗-HBe阳转,则提示肝脏大致无损害,传染性降低或基本消失。还有人提出抗-HBe为保护性抗体,其阳性提示感染终止,短期内肝炎可获治愈。近年来,随着检测水平的提高,对抗-HBe有了新的认识。本文就30例抗-HBe阳性慢活肝的临床观察,进一步探讨抗-HBe的临床意义。 It is generally considered that the presence of HBeAg in the serum of patients with hepatitis B indicates more severe liver lesion activity and damage. When HBeAg disappears, anti-HBe is positive, then the liver is almost not damaged, reducing or almost disappearing. Others have suggested that anti-HBe as a protective antibody, the positive prompts the termination of infection, hepatitis will be cured in the short term. In recent years, with the detection level increased, anti-HBe has a new understanding. In this paper, 30 cases of anti-HBe positive slow liver clinical observation to further explore the clinical significance of anti-HBe.