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本文报告采用血浆置换疗法(PE)治疗3例急进性肾小球肾炎(RPGN)的疗效。3例肾功能均有明显改善,Scr 下降,Ccr 上升;2例尿蛋白排出减少,1例增加。1例存活,随访2年一般情况良好;1例出院4月后死亡;1例死于霉菌感染。PE 简单易行,副作用少,对RPGN 可能是一种行之有效的治疗途径,值得进一步探索。
This article reports the use of plasma exchange therapy (PE) in the treatment of 3 patients with acute glomerulonephritis (RPGN). 3 cases of renal function were significantly improved, Scr decreased, Ccr increased; 2 cases of urinary protein excretion decreased in 1 case increased. One patient survived and was followed up for 2 years generally in good condition; one patient died after 4 months of discharge and one patient died of a mold infection. PE is simple and has few side effects. It may be an effective treatment for RPGN and worth further exploration.