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据英国科学家报道,随着医学的发展,对某些肺疾病有了新的治疗手段。一些我们以前难以治疗的疾病,将有望治愈。 基因治疗是治疗肺脏疾病的最新趋向。它可以取代、改变和抑制有关的基因。α_2—抗胰蛋白酶缺乏症和囊性肺纤维化是最常见和最单一的致死性基因性疾病。现在有些医生已对成人呼吸窘迫综合征(ARDS)、慢性阻塞性肺病(COPD)和哮喘患者试用基因治疗。抑制抗弹性酶基因可以控制由于肺损伤后发生的蛋白酶导致的肺气肿;又例如抑制抗炎性细胞因子的基因、抑制炎症性转录因子和抑制NF—kB都是治疗囊性肺纤维化的基因疗法。 哮喘目前被认为是一种受基因IL—5驱使的嗜酸粒细胞
According to British scientists, with the development of medicine, there are new treatments for some lung diseases. Some of the diseases we have previously treated with difficulty are expected to be cured. Gene therapy is the latest trend in the treatment of lung disease. It can replace, change and inhibit the related genes. Alpha-2 antitrypsin deficiency and cystic fibrosis are the most common and single fatal genetic diseases. Now some doctors have tried gene therapy on adult respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD) and asthma. Inhibition of the anti-elastase gene can control emphysema due to proteases that occur after lung injury; and for example, genes that inhibit anti-inflammatory cytokines, inhibition of inflammatory transcription factors and inhibition of NF-kB are all treatments for cystic pulmonary fibrosis Gene therapy. Asthma is currently thought to be an eosinophil driven by the gene IL-5