作者对52例患有心力衰竭的先天性心脏病(CHF)的乳儿,测定了血清β_2微球蛋白(β_2-m)及血清地高辛浓度。A组20例为重症心力衰竭,主要是住院患儿,体重在标准体重的70%以下。B组32例为轻症心力衰竭,是口服维持量地高辛的门诊患儿,体重在标准体重的71%以上。血清β_2-m是在地高辛用药5小时以后检测。A组患儿血清β_2-m值为1.4～8.5mg/l,(平均值为3.7±1.7mg/l),B组患儿则为0.9～3.8mg/l, The authors measured serum β 2-microglobulin (β 2-m) and serum digoxin concentrations in 52 infants with heart failure congenital heart disease (CHF). A group of 20 patients with severe heart failure, mainly hospitalized children, weighing less than 70% of the standard weight. B group of 32 patients with mild heart failure, oral administration of digoxin to maintain the amount of children, weighing more than 71% of the standard weight. Serum β_2-m was measured 5 hours after digoxin treatment. Serum β_2-m in group A was 1.4-8.5 mg / l (mean ± SD 3.7 ± 1.7 mg / l) and group B was 0.9-3.8 mg / l