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有人提出,血小板对类风湿性关节炎的产生和形成可能有重要作用。在病人的血浆和滑液中,5-羟色胺((?)-HT)的转换率亦有改变。5-HT被认为可增加免疫复合物的沉积,故可能有促进炎症过程的作用。另有报告提出,类风湿性关节炎病人在饥饿时临床症状改善,而当摄取某些食物后则关节炎加剧。本文作者研究了类风湿性关节炎病人于摄取不能耐受的食物时血小板释放5-HT的可能性。 7例类风湿性关节炎病人在摄取不能耐受的食物后1～4小时,均有关节炎的表现,并持续至18个小时。摄食前,病人组和对照组在富含血小板的血浆中
It has been suggested that platelets may play an important role in the production and formation of rheumatoid arthritis. In patients with plasma and synovial fluid, serotonin ((?) - HT) conversion rate also changed. 5-HT is thought to increase the deposition of immune complexes and therefore may have an effect on the inflammatory process. Another report suggested that patients with rheumatoid arthritis improved in clinical symptoms of hunger, and arthritis increased when certain foods were taken. The authors investigated the possibility of platelet release of 5-HT in patients with rheumatoid arthritis when ingesting intolerable food. Seven patients with rheumatoid arthritis showed signs of arthritis 1 to 4 hours after ingestion of intolerable food and continued for up to 18 hours. Before feeding, the patient group and the control group were in platelet-rich plasma