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目的分析多库酯钠联合聚乙二醇在慢性便秘患者肠道准备中的应用效果。方法回顾性分析358例行结肠镜检查的便秘患者,根据肠道准备方法不同分为2组,观察组184例在服用多库酯钠3 d后,服用聚乙二醇;对照组174例直接服用聚乙二醇,比较2组患者首次排便时间、总大便次数、排便总时长、肠道清洁度及服药过程中的不良反应。结果观察组首次排便时间、总大便次数、排便总时长、肠道清洁度均优于对照组,差异均有统计学意义(P<0.05)。观察组不良反应率为15.22%,对照组为21.26%,2组比较差异无统计学意义(χ2=2.201,P>0.05)。结论多库酯钠联合聚乙二醇在便秘患者肠镜检查前肠道准备中的效果优于单用聚乙二醇。
Objective To analyze the effect of docusate sodium combined with polyethylene glycol in the intestinal preparation of patients with chronic constipation. Methods A retrospective analysis of 358 cases of constipation patients undergoing colonoscopy was divided into two groups according to different intestinal preparation methods. The observation group received oral administration of docusate sodium for 3 d, and the control group of 174 patients Taking polyethylene glycol, the first defecation time, the total stool frequency, the total defecation time, the intestinal tract cleanliness and the adverse reactions during the medication were compared between the two groups. Results The first defecation time, the total stool frequency, the total defecation duration and the intestinal cleanliness in the observation group were all better than those in the control group (P <0.05). Adverse reaction rate was 15.22% in the observation group and 21.26% in the control group. There was no significant difference between the two groups (χ2 = 2.201, P> 0.05). Conclusions Docusate sodium plus polyethylene glycol is superior to single polyethylene glycol in bowel preparation before colonoscopy in patients with constipation.