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Sjogren 综合征是一种慢性自身免疫病,由于淋巴细胞浸润到涎腺、泪腺和其他外分泌腺而导致口腔干燥及干燥性角膜结膜炎,它可分为原发性及继发性两种。主要发生在40～50岁的妇女,儿童病例则属少见,据文献记载有21例,本文报告8例。本组8例,女孩6例,男孩2例,发病年龄平均8.2岁,诊断年龄平均11.7岁。5例开始表现为各种自身免疫现象,如抗球蛋白抗体阳性的溶血性贫血,血小板减少症,高丙球蛋白血症性紫斑,盘状红斑狼疮及雷诺氏现象;另3例开始为复发性腮腺肿
Sjogren’s syndrome is a chronic autoimmune disease that can be classified into primary and secondary due to lymphoid infiltration into the salivary gland, lacrimal gland and other exocrine glands leading to dry mouth and dry keratoconjunctivitis. Occurs mainly in women aged 40 to 50 years, while rare cases of children, according to the literature records of 21 cases, the paper reports 8 cases. The group of 8 patients, 6 girls, 2 boys, the average age of onset of 8.2 years, the average age of diagnosis of 11.7 years. 5 cases began to show a variety of autoimmune phenomena, such as anti-globulin antibody-positive hemolytic anemia, thrombocytopenia, hypergammaglobulinemia, discoid lupus erythematosus and Raynaud’s phenomenon; the other three cases began to recurrent parotid gland swollen