论文部分内容阅读
目的探讨不典型鳞状细胞(ASCUS)的临床意义、进一步处理措施以及高危型人乳头病毒（HR-HPV）检测的分流作用。方法对宫颈薄层液基细胞学诊断为ASCUS的160例患者分别进行HR-HPV检测、阴道镜下活组织检查。结果在HR-HPV阳性组高级别CIN检出率为14.46%,在HR-HPV阴性组高级别CIN检出率为1.30%,两组间差异有统计学意义(x2=1，<0.05)。HPV在ASCUS患者中检测高级别CIN和浸润癌的敏感度和特异度为：92.31%和86.39%，阳性预测值和阴性预测值为：14.46%和99.21%。结论 HR-HPV阳性的ASCUS患者高级别CIN发生率高,应行阴道镜检查，HR-HPV阴性的ASCUS患者发生高级别CIN的风险低，可随诊。“,”Objective To investigate the clinical significance of atypical squamous cel of undetermined significancein (ASCUS)cervical smear,its management strategies and the value of high rist human papil omavirus (HR-HPV)test.Methods 160 patients with ASCUS tested by thin-prep-1iquid-based cytology were undergone with HR-HPV testing,colposcopy and cervical biopsies.Results The frequency of high level CIN in HR-HPV positive group and negative group was 14.46%and 1.30%.The dif erence was statistical y significant (x2=1,<0.05).The sensitivity and specificity of HR-HPV-positive in diagnosing high level CIN and invasive carcinoma were 92.31%and 86.39%,the positive predictive value and negative predictive value was 14.46%and 99.21%.Conclusion HR-HPV positive patients with ASCUS high incidence of high level CIN,should undergo with colposcopy,HR-HPV negative patients with ASCUS,the risk of CIN can fol ow up.