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目的:探究在不稳定性心绞痛的临床治疗过程中,对比分析不同剂量的阿托伐他汀的临床效果。方法:将该院自2014年6月至2015年2月期间收治的78例不稳定性心绞痛患者作为研究对象,随机分为试验组和对照组,对比两组患者应用不同治疗方案的临床效果。结果:治疗结束后,试验组患者发作心绞痛等症状明显改善,其总有效率为94.9%(37/39),明显优于对照组(P<0.05)。经过不同剂量的阿托伐他汀分组治疗后,试验组患者的CRP和LDL-C明显改善,且改善幅度显著优于经小剂量治疗的对照组(P<0.05)。结论:在不稳定性心绞痛的临床治疗过程中,应用大剂量的阿托伐他汀的疗效较好,可显著改善患者的心绞痛症状并改善高血脂状况,应广泛推广。
Objective: To investigate the clinical effects of different doses of atorvastatin during clinical treatment of unstable angina. Methods: Seventy-eight patients with unstable angina pectoris admitted from June 2014 to February 2015 in our hospital were randomly divided into experimental group and control group. The clinical effects of different treatment regimens were compared between the two groups. Results: At the end of treatment, angina pectoris and other symptoms in the experimental group were significantly improved. The total effective rate was 94.9% (37/39), which was significantly better than that of the control group (P <0.05). After different doses of atorvastatin group, CRP and LDL-C in the test group were significantly improved, and the improvement range was significantly better than the control group treated with low dose (P <0.05). Conclusion: In the course of clinical treatment of unstable angina pectoris, high dose of atorvastatin has a good curative effect, which can significantly improve patients’ angina pectoris symptoms and improve hyperlipidemia, and should be widely promoted.