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目的了解并分析奥扎格雷钠治疗急性脑梗塞的临床疗效。方法选用一般情况具有可比性的急性脑梗塞患者将其随机分为治疗组39例,对照组40例,进行临床及实验指标观察并比较分析。结果治疗组和对照组的临床总有效率分别为92%和70%(P<0.01),神经功能缺损评分明显减少,血小板凝聚率、全血程度明显降低(P<0.01),两组纤维蛋白原的变化不显著(P>0.05)。结论奥扎格雷钠治疗急性脑梗塞安全有效,值得临床推广应用。
Objective To understand and analyze the clinical efficacy of ozagrel sodium in the treatment of acute cerebral infarction. Methods Acute cerebral infarction patients with comparable general conditions were randomly divided into treatment group (39 cases) and control group (40 cases). The clinical and experimental indexes were observed and compared. Results The total clinical effective rates of the treatment group and the control group were 92% and 70% respectively (P <0.01), the score of neurological deficit was significantly decreased, the rate of platelet aggregation and whole blood was significantly decreased (P <0.01) The original change was not significant (P> 0.05). Conclusion Ozagrel sodium is safe and effective in the treatment of acute cerebral infarction. It is worthy of clinical application.