论文部分内容阅读
目的:观察强肌健力方对脾肾两虚大鼠的脾脏、胸腺、肾上腺超微结构的影响,及其对脾肾两虚证的改善作用。方法:将SD大鼠60只随机分为正常对照组、模型组、强肌健力组、右归丸组、强肌右归丸组。前期采用大黄复制脾虚模型,后期采用氢化可的松复制肾虚模型,分别给予蒸馏水、强肌健力方、右归丸灌胃。比较各组动物脾脏、胸腺、肾上腺超微结构的改变。结果:正常对照组脾小体中淋巴细胞、胸腺皮质淋巴细胞、肾上腺皮质细胞的超微结构均正常,而模型组大鼠的脾脏、胸腺、肾上腺超微结构均有明显的损伤现象,各用药组均使已受损伤的各脏器的超微结构得以修复,其中强肌右归丸组使受损的各脏器的超微结构恢复到最接近正常水平。结论:强肌健力方对脾肾两虚证大鼠受损的脾脏、胸腺、肾上腺组织具有一定的保护作用。
Objective: To observe the effect of Qiangji Jianli Recipe on the ultrastructure of spleen, thymus and adrenal of rats with spleen and kidney deficiency, and to improve the effect of deficiency of both spleen and kidney. Methods: Sixty SD rats were randomly divided into normal control group, model group, Qiangji Jianli group, Youguiwan group and Qiangji Yougui pill group. Early use of rhubarb copy spleen deficiency model, later use of hydrocortisone copy kidney deficiency model, were given distilled water, strong muscle Jianli Fang, You Gui Wan intragastric administration. The ultrastructural changes in spleen, thymus and adrenal of each group were compared. Results: The ultrastructure of lymphocytes, thymic cortical lymphocytes and adrenocortical cells in spleen bodies of normal control group were all normal. However, the ultrastructure of spleen, thymus and adrenal of model group rats were obviously damaged. The ultrastructures of the damaged organs were all repaired. Among them, the Qianggu Yougui pill group restored the ultrastructure of the damaged organs to the nearest normal level. Conclusion: Qiangji Jianli Recipe has a protective effect on the damaged spleen, thymus and adrenal tissue in rats with spleen and kidney deficiency.