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食管化学性烧伤系由于误服化学制剂酸、碱或含酸、碱的一些制品如洗涤剂,消毒剂等所引起。【病理改变】食管碱烧伤最常见。有人作实验性食管碱烧伤观察,肉眼所见反应包括肌肉痉挛,括约肌功能紊乱,剧烈的逆蠕动,胃内容反流等;显微改变在烧伤后1~5天粘膜表面皂化、栓塞、坏死以及细菌侵犯;4~7天出现坏死,组织脱落;8~12天后在坏死组织区出现成纤维细胞,坏死组织逐渐由胶元纤维所取代在7~21天是食管壁最脆弱的时期,大约至烧伤后21天,出现食管狭窄症状,28天以后狭窄完全形成。狭窄也可以发生在烧伤后一周以内,这主要
Esophageal chemical burns due to mistakenly due to chemical agents acid, alkali or acid, alkali, some products such as detergents, disinfectants caused. Pathological changes esophageal alkali burn the most common. Some people for experimental observation of esophageal alkali burn, macroscopic findings include muscle spasms, sphincter dysfunction, severe reverse peristalsis, reflux of gastric contents; microscopic changes in the burn 1 to 5 days after the mucosal surface saponification, embolization, necrosis and Bacterial invasion; 4 to 7 days of necrosis, tissue shedding; 8 to 12 days in the necrotic tissue area fibroblasts, necrotic tissue gradually replaced by collagen fibers in 7 to 21 days is the most vulnerable esophageal period, about To 21 days after burn, the symptoms of esophageal stenosis, stenosis completely formed after 28 days. Stenosis can also occur within a week after the burn, mainly